About Transcription factor 15
Transcription factor 15 (TCF15) is a protein
from Homo sapiens identified by UniProt accession
Q12870, 199 residues long.
MolForge cross-references it against 0 known binders and
26 disease associations.
Target properties
| Protein name | Transcription factor 15 |
|---|
| UniProt accession | Q12870 |
|---|
| Gene | TCF15 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 199 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (26)
Diseases linked to this target (Open Targets).
- birth weight · score 0.13
- exhaustion · score 0.09
- metatropic dysplasia · score 0.03
- Dyggve-Melchior-Clausen disease · score 0.03
- fibrochondrogenesis 1 · score 0.03
- Poland syndrome · score 0.03
- acute myeloid leukemia · score 0.03
- Recurrent aphthous stomatitis · score 0.02
- juvenile dermatomyositis · score 0.01
- infection · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q12870-F1 | alphafold | PREDICTED | 68.80 | — |
Amino-acid sequence (199 residues)
MAFALLRPVG AHVLYPDVRL LSEDEENRSE SDASDQSFGC CEGPEAARRG PGPGGGRRAG GGGGAGPVVV VRQRQAANAR ERDRTQSVNT AFTALRTLIP TEPVDRKLSK IETVRLASSY IAHLANVLLL GDSADDGQPC FRAAGSAKGA VPAAADGGRQ PRSICTFCLS NQRKGGGRRD LGGSCLKVRG VAPLRGPRR
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