About Transcription initiation factor TFIID subunit 10
Transcription initiation factor TFIID subunit 10 (TAF10) is a protein
from Homo sapiens identified by UniProt accession
Q12962, 218 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | Transcription initiation factor TFIID subunit 10 |
|---|
| UniProt accession | Q12962 |
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| Gene | TAF10 |
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| Organism | Homo sapiens |
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| Length | 218 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (21)
Diseases linked to this target (Open Targets).
- HIV infection · score 0.58
- familial hypertrophic cardiomyopathy · score 0.19
- lung adenocarcinoma · score 0.18
- head and neck squamous cell carcinoma · score 0.18
- Abnormality of the cardiovascular system · score 0.15
- dilated cardiomyopathy · score 0.12
- Prolonged QT interval · score 0.12
- hemoglobin measurement · score 0.04
- neoplasm · score 0.03
- cancer · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q12962-F1 | alphafold | PREDICTED | 66.91 | — |
Amino-acid sequence (218 residues)
MSCSGSGADP EAAPASAASA PGPAPPVSAP AALPSSTAAE NKASPAGTAG GPGAGAAAGG TGPLAARAGE PAERRGAAPV SAGGAAPPEG AISNGVYVLP SAANGDVKPV VSSTPLVDFL MQLEDYTPTI PDAVTGYYLN RAGFEASDPR IIRLISLAAQ KFISDIANDA LQHCKMKGTA SGSSRSKSKD RKYTLTMEDL TPALSEYGIN VKKPHYFT
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