About Vesicle transport protein SEC20
Vesicle transport protein SEC20 (BNIP1) is a protein
from Homo sapiens identified by UniProt accession
Q12981, 228 residues long.
MolForge cross-references it against 0 known binders and
35 disease associations.
Target properties
| Protein name | Vesicle transport protein SEC20 |
|---|
| UniProt accession | Q12981 |
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| Gene | BNIP1 |
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| Organism | Homo sapiens |
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| Length | 228 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (35)
Diseases linked to this target (Open Targets).
- infantile hypertrophic pyloric stenosis · score 0.27
- PR interval · score 0.20
- platelet count · score 0.14
- spondyloepiphyseal dysplasia congenita · score 0.12
- open-angle glaucoma · score 0.12
- cystatin C measurement · score 0.10
- body height · score 0.09
- pulse pressure measurement · score 0.08
- self reported educational attainment · score 0.08
- lean body mass · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q12981-F1 | alphafold | PREDICTED | 80.48 | — |
Amino-acid sequence (228 residues)
MAAPQDVHVR ICNQEIVKFD LEVKALIQDI RDCSGPLSAL TELNTKVKEK FQQLRHRIQD LEQLAKEQDK ESEKQLLLQE VENHKKQMLS NQASWRKANL TCKIAIDNLE KAELLQGGDL LRQRKTTKES LAQTSSTITE SLMGISRMMA QQVQQSEEAM QSLVTSSRTI LDANEEFKSM SGTIQLGRKL ITKYNRRELT DKLLIFLALA LFLATVLYIV KKRLFPFL
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