About Cell division cycle protein 16 homolog
Cell division cycle protein 16 homolog (CDC16) is a protein
from Homo sapiens identified by UniProt accession
Q13042, 620 residues long.
MolForge cross-references it against 0 known binders and
51 disease associations.
Target properties
| Protein name | Cell division cycle protein 16 homolog |
|---|
| UniProt accession | Q13042 |
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| Gene | CDC16 |
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| Organism | Homo sapiens |
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| Length | 620 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (51)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.31
- sex hormone-binding globulin measurement · score 0.30
- body height · score 0.30
- forced expiratory volume · score 0.27
- appendicular lean mass · score 0.27
- pulse pressure measurement · score 0.26
- body weight · score 0.24
- hypertension · score 0.23
- sitting height measurement · score 0.22
- vital capacity · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13042-F1 | alphafold | PREDICTED | 78.85 | — |
Amino-acid sequence (620 residues)
MNLERLRKRV RQYLDQQQYQ SALFWADKVA SLSREEPQDI YWLAQCLYLT AQYHRAAHAL RSRKLDKLYE ACRYLAARCH YAAKEHQQAL DVLDMEEPIN KRLFEKYLKD ESGFKDPSSD WEMSQSSIKS SICLLRGKIY DALDNRTLAT YSYKEALKLD VYCFEAFDLL TSHHMLTAQE EKELLESLPL SKLCNEEQEL LRFLFENKLK KYNKPSETVI PESVDGLQEN LDVVVSLAER HYYNCDFKMC YKLTSVVMEK DPFHASCLPV HIGTLVELNK ANELFYLSHK LVDLYPSNPV SWFAVGCYYL MVGHKNEHAR RYLSKATTLE KTYGPAWIAY GHSFAVESEH DQAMAAYFTA AQLMKGCHLP MLYIGLEYGL TNNSKLAERF FSQALSIAPE DPFVMHEVGV VAFQNGEWKT AEKWFLDALE KIKAIGNEVT VDKWEPLLNN LGHVCRKLKK YAEALDYHRQ ALVLIPQNAS TYSAIGYIHS LMGNFENAVD YFHTALGLRR DDTFSVTMLG HCIEMYIGDS EAYIGADIKD KLKCYDFDVH TMKTLKNIIS PPWDFREFEV EKQTAEETGL TPLETSRKTP DSRPSLEETF EIEMNESDMM LETSMSDHST
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