About Pregnancy-specific beta-1-glycoprotein 7
Pregnancy-specific beta-1-glycoprotein 7 (PSG7) is a protein
from Homo sapiens identified by UniProt accession
Q13046, 419 residues long.
MolForge cross-references it against 0 known binders and
48 disease associations.
Target properties
| Protein name | Pregnancy-specific beta-1-glycoprotein 7 |
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| UniProt accession | Q13046 |
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| Gene | PSG7 |
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| Organism | Homo sapiens |
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| Length | 419 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (48)
Diseases linked to this target (Open Targets).
- visual perception measurement · score 0.10
- preeclampsia · score 0.07
- obesity due to melanocortin 4 receptor deficiency · score 0.06
- birth weight · score 0.05
- papillary thyroid carcinoma · score 0.05
- LIPE-related familial partial lipodystrophy · score 0.04
- obesity due to leptin receptor gene deficiency · score 0.04
- AXIN2-related attenuated familial adenomatous polyposis · score 0.04
- PLIN1-related familial partial lipodystrophy · score 0.04
- obesity due to prohormone convertase I deficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13046-F1 | alphafold | PREDICTED | 88.14 | — |
Amino-acid sequence (419 residues)
MGPLSAPPCT QHITWKGLLL TASLLNFWNP PTTAQVTIEA QPPKVSEGKD VLLLVHNLPQ NLTGYIWYKG QIRDLYHYVT SYIVDGQIIK YGPAYSGRET VYSNASLLIQ NVTQEDTGSY TLHIIKRGDG TGGVTGRFTF TLYLETPKPS ISSSNFNPRE ATEAVILTCD PETPDASYLW WMNGQSLPMT HSLQLSETNR TLYLFGVTNY TAGPYECEIR NPVSASRSDP VTLNLLPKLP KPYITINNLN PRENKDVSTF TCEPKSENYT YIWWLNGQSL PVSPRVKRRI ENRILILPSV TRNETGPYQC EIRDRYGGIR SDPVTLNVLY GPDLPRIYPS FTYYHSGQNL YLSCFADSNP PAQYSWTING KFQLSGQKLS IPQITTKHSG LYACSVRNSA TGKESSKSVT VRVSDWTLP
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