About Large ribosomal subunit protein bL28m
Large ribosomal subunit protein bL28m (MRPL28) is a protein
from Homo sapiens identified by UniProt accession
Q13084, 256 residues long.
MolForge cross-references it against 0 known binders and
24 disease associations.
Target properties
| Protein name | Large ribosomal subunit protein bL28m |
|---|
| UniProt accession | Q13084 |
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| Gene | MRPL28 |
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| Organism | Homo sapiens |
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| Length | 256 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (24)
Diseases linked to this target (Open Targets).
- fat body mass · score 0.18
- blood protein measurement · score 0.12
- lean body mass · score 0.10
- appendicular lean mass · score 0.10
- mean corpuscular hemoglobin · score 0.09
- forced expiratory volume · score 0.08
- heel bone mineral density · score 0.07
- bone quantitative ultrasound measurement · score 0.07
- hair shape measurement · score 0.06
- bone density · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13084-F1 | alphafold | PREDICTED | 92.31 | — |
Amino-acid sequence (256 residues)
MPLHKYPVWL WKRLQLREGI CSRLPGHYLR SLEEERTPTP VHYRPHGAKF KINPKNGQRE RVEDVPIPIY FPPESQRGLW GGEGWILGQI YANNDKLSKR LKKVWKPQLF EREFYSEILD KKFTVTVTMR TLDLIDEAYG LDFYILKTPK EDLCSKFGMD LKRGMLLRLA RQDPQLHPED PERRAAIYDK YKEFAIPEEE AEWVGLTLEE AIEKQRLLEE KDPVPLFKIY VAELIQQLQQ QALSEPAVVQ KRASGQ
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