Lymphocyte cytosolic protein 2 (LCP2)

About Lymphocyte cytosolic protein 2

Lymphocyte cytosolic protein 2 (LCP2) is a protein from Homo sapiens identified by UniProt accession Q13094, 533 residues long. MolForge cross-references it against 0 known binders and 348 disease associations.

Target properties

Protein name	Lymphocyte cytosolic protein 2
UniProt accession	Q13094
Gene	LCP2
Organism	Homo sapiens
Length	533 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (348)

Diseases linked to this target (Open Targets).

immunodeficiency 81 · score 0.52
eosinophil count · score 0.45
mean platelet volume · score 0.43
eosinophil percentage of leukocytes · score 0.35
breast adenocarcinoma · score 0.25
neurodegenerative disease · score 0.24
inflammatory bowel disease · score 0.17
head and neck squamous cell carcinoma · score 0.12
lung adenocarcinoma · score 0.12
early-onset non-syndromic cataract · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q13094-F1	alphafold	PREDICTED	62.95	—

Amino-acid sequence (533 residues)

MALRNVPFRS EVLGWDPDSL ADYFKKLNYK DCEKAVKKYH IDGARFLNLT ENDIQKFPKL RVPILSKLSQ EINKNEERRS IFTRKPQVPR FPEETESHEE DNGGWSSFEE DDYESPNDDQ DGEDDGDYES PNEEEEAPVE DDADYEPPPS NDEEALQNSI LPAKPFPNSN SMYIDRPPSG KTPQQPPVPP QRPMAALPPP PAGRNHSPLP PPQTNHEEPS RSRNHKTAKL PAPSIDRSTK PPLDRSLAPF DREPFTLGKK PPFSDKPSIP AGRSLGEHLP KIQKPPLPPT TERHERSSPL PGKKPPVPKH GWGPDRREND EDDVHQRPLP QPALLPMSSN TFPSRSTKPS PMNPLPSSHM PGAFSESNSS FPQSASLPPY FSQGPSNRPP IRAEGRNFPL PLPNKPRPPS PAEEENSLNE EWYVSYITRP EAEAALRKIN QDGTFLVRDS SKKTTTNPYV LMVLYKDKVY NIQIRYQKES QVYLLGTGLR GKEDFLSVSD IIDYFRKMPL LLIDGKNRGS RYQCTLTHAA GYP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards