Zinc finger protein 154 (ZNF154)

About Zinc finger protein 154

Zinc finger protein 154 (ZNF154) is a protein from Homo sapiens identified by UniProt accession Q13106, 437 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.

Target properties

Protein name	Zinc finger protein 154
UniProt accession	Q13106
Gene	ZNF154
Organism	Homo sapiens
Length	437 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (42)

Diseases linked to this target (Open Targets).

neoplasm · score 0.11
cancer · score 0.09
esophageal squamous cell carcinoma · score 0.07
gonorrhea · score 0.07
head and neck squamous cell carcinoma · score 0.07
total cholesterol measurement · score 0.03
allergic rhinitis · score 0.02
pancreatic neoplasm · score 0.02
lung adenocarcinoma · score 0.02
renal cell carcinoma · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q13106-F1	alphafold	PREDICTED	70.99	—

Amino-acid sequence (437 residues)

MAAATLRTPT QGTVTFEDVA VHFSWEEWGL LDEAQRCLYR DVMLENLALL TSLDVHHQKQ HLGEKHFRSN VGRALFVKTC TFHVSGEPST CREVGKDFLA KLGFLHQQAA HTGEQSNSKS DGGAISHRGK THYNCGEHTK AFSGKHTLVQ QQRTLTTERC YICSECGKSF SKSYSLNDHW RLHTGEKPYE CRECGKSFRQ SSSLIQHRRV HTAVRPHECD ECGKLFSNKS NLIKHRRVHT GERPYECSEC GKSFSQRSAL LQHRGVHTGE RPYECSECGK FFTYHSSLIK HQKVHSGSRP YECSECGKSF SQNSSLIEHH RVHTGERPYK CSECGKSFSQ RSALLQHRGV HTGERPYECS ECGKFFPYSS SLRKHQRVHT GSRPYECSEC GKSFTQNSGL IKHRRVHTGE KPYECTECGK SFSHNSSLIK HQRIHSR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards