PDZK1-interacting protein 1 (PDZK1IP1)

About PDZK1-interacting protein 1

PDZK1-interacting protein 1 (PDZK1IP1) is a protein from Homo sapiens identified by UniProt accession Q13113, 114 residues long. MolForge cross-references it against 0 known binders and 183 disease associations.

Target properties

Protein name	PDZK1-interacting protein 1
UniProt accession	Q13113
Gene	PDZK1IP1
Organism	Homo sapiens
Length	114 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (183)

Diseases linked to this target (Open Targets).

mean corpuscular hemoglobin · score 0.33
mean corpuscular volume · score 0.22
Red cell distribution width · score 0.17
mean reticulocyte volume · score 0.16
mean corpuscular hemoglobin concentration · score 0.14
neoplasm · score 0.11
hepatocellular carcinoma · score 0.09
body mass index · score 0.09
platelet count · score 0.08
dental caries · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q13113-F1	alphafold	PREDICTED	64.77	—

Amino-acid sequence (114 residues)

MSALSLLILG LLTAVPPASC QQGLGNLQPW MQGLIAVAVF LVLVAIAFAV NHFWCQEEPE PAHMILTVGN KADGVLVGTD GRYSSMAASF RSSEHENAYE NVPEEEGKVR STPM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards