About BMP and activin membrane-bound inhibitor homolog
BMP and activin membrane-bound inhibitor homolog (BAMBI) is a protein
from Homo sapiens identified by UniProt accession
Q13145, 260 residues long.
MolForge cross-references it against 0 known binders and
194 disease associations.
Target properties
| Protein name | BMP and activin membrane-bound inhibitor homolog |
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| UniProt accession | Q13145 |
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| Gene | BAMBI |
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| Organism | Homo sapiens |
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| Length | 260 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (194)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.41
- mean corpuscular hemoglobin concentration · score 0.36
- cataract · score 0.36
- sitting height measurement · score 0.31
- mean corpuscular hemoglobin · score 0.30
- serum urea measurement · score 0.29
- blood urea nitrogen measurement · score 0.28
- appendicular lean mass · score 0.26
- Age-related cataract · score 0.25
- lens disease · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13145-F1 | alphafold | PREDICTED | 64.63 | — |
Amino-acid sequence (260 residues)
MDRHSSYIFI WLQLELCAMA VLLTKGEIRC YCDAAHCVAT GYMCKSELSA CFSRLLDPQN SNSPLTHGCL DSLASTTDIC QAKQARNHSG TTIPTLECCH EDMCNYRGLH DVLSPPRGEA SGQGNRYQHD GSRNLITKVQ ELTSSKELWF RAAVIAVPIA GGLILVLLIM LALRMLRSEN KRLQDQRQQM LSRLHYSFHG HHSKKGQVAK LDLECMVPVS GHENCCLTCD KMRQADLSND KILSLVHWGM YSGHGKLEFV
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