Heterogeneous nuclear ribonucleoprotein A0 (HNRNPA0)

About Heterogeneous nuclear ribonucleoprotein A0

Heterogeneous nuclear ribonucleoprotein A0 (HNRNPA0) is a protein from Homo sapiens identified by UniProt accession Q13151, 305 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.

Target properties

Protein name	Heterogeneous nuclear ribonucleoprotein A0
UniProt accession	Q13151
Gene	HNRNPA0
Organism	Homo sapiens
Length	305 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (36)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.35
age at menarche · score 0.08
cancer · score 0.08
neoplasm · score 0.08
blood pressure · score 0.05
heart failure · score 0.04
hemoglobin measurement · score 0.02
allergic disease · score 0.02
substance abuse · score 0.02
attention deficit hyperactivity disorder · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q13151-F1	alphafold	PREDICTED	71.47	—

Amino-acid sequence (305 residues)

MENSQLCKLF IGGLNVQTSE SGLRGHFEAF GTLTDCVVVV NPQTKRSRCF GFVTYSNVEE ADAAMAASPH AVDGNTVELK RAVSREDSAR PGAHAKVKKL FVGGLKGDVA EGDLIEHFSQ FGTVEKAEII ADKQSGKKRG FGFVYFQNHD AADKAAVVKF HPIQGHRVEV KKAVPKEDIY SGGGGGGSRS SRGGRGGRGR GGGRDQNGLS KGGGGGYNSY GGYGGGGGGG YNAYGGGGGG SSYGGSDYGN GFGGFGSYSQ HQSSYGPMKS GGGGGGGGSS WGGRSNSGPY RGGYGGGGGY GGSSF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards