About Peroxiredoxin-4
Peroxiredoxin-4 (PRDX4) is a protein
from Homo sapiens identified by UniProt accession
Q13162, 271 residues long.
MolForge cross-references it against 0 known binders and
246 disease associations.
Target properties
| Protein name | Peroxiredoxin-4 |
|---|
| UniProt accession | Q13162 |
|---|
| Gene | PRDX4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 271 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (246)
Diseases linked to this target (Open Targets).
- Neurodevelopmental delay · score 0.12
- neoplasm · score 0.11
- lung adenocarcinoma · score 0.09
- polycystic ovary syndrome · score 0.09
- type 2 diabetes mellitus · score 0.08
- glioblastoma multiforme · score 0.08
- cancer · score 0.08
- immature platelet fraction · score 0.08
- colorectal carcinoma · score 0.08
- azoospermia · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13162-F1 | alphafold | PREDICTED | 84.33 | — |
Amino-acid sequence (271 residues)
MEALPLLAAT TPDHGRHRRL LLLPLLLFLL PAGAVQGWET EERPRTREEE CHFYAGGQVY PGEASRVSVA DHSLHLSKAK ISKPAPYWEG TAVIDGEFKE LKLTDYRGKY LVFFFYPLDF TFVCPTEIIA FGDRLEEFRS INTEVVACSV DSQFTHLAWI NTPRRQGGLG PIRIPLLSDL THQISKDYGV YLEDSGHTLR GLFIIDDKGI LRQITLNDLP VGRSVDETLR LVQAFQYTDK HGEVCPAGWK PGSETIIPDP AGKLKYFDKL N
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