About Solute carrier family 13 member 2
Solute carrier family 13 member 2 (SLC13A2) is a protein
from Homo sapiens identified by UniProt accession
Q13183, 592 residues long.
MolForge cross-references it against 0 known binders and
116 disease associations.
Target properties
| Protein name | Solute carrier family 13 member 2 |
|---|
| UniProt accession | Q13183 |
|---|
| Gene | SLC13A2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 592 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (116)
Diseases linked to this target (Open Targets).
- cataract · score 0.09
- blood urea nitrogen measurement · score 0.09
- pentosuria · score 0.07
- uridine-cytidineuria · score 0.07
- isolated sedoheptulokinase deficiency · score 0.07
- familial idiopathic steroid-resistant nephrotic syndrome · score 0.07
- nephrotic syndrome · score 0.06
- seizures-intellectual disability due to hydroxylysinuria syndrome · score 0.06
- focal segmental glomerulosclerosis · score 0.06
- carnosinemia · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13183-F1 | alphafold | PREDICTED | 83.23 | — |
Amino-acid sequence (592 residues)
MATCWQALWA YRSYLIVFFV PILLLPLPIL VPSKEAYCAY AIILMALFWC TEALPLAVTA LFPLILFPMM GIVDASEVAV EYLKDSNLLF FGGLLVAIAV EHWNLHKRIA LRVLLIVGVR PAPLILGFML VTAFLSMWIS NTATSAMMVP IAHAVLDQLH SSQASSNVEE GSNNPTFELQ EPSPQKEVTK LDNGQALPVT SASSEGRAHL SQKHLHLTQC MSLCVCYSAS IGGIATLTGT APNLVLQGQI NSLFPQNGNV VNFASWFSFA FPTMVILLLL AWLWLQILFL GFNFRKNFGI GEKMQEQQQA AYCVIQTEHR LLGPMTFAEK AISILFVILV LLWFTREPGF FLGWGNLAFP NAKGESMVSD GTVAIFIGII MFIIPSKFPG LTQDPENPGK LKAPLGLLDW KTVNQKMPWN IVLLLGGGYA LAKGSERSGL SEWLGNKLTP LQSVPAPAIA IILSLLVATF TECTSNVATT TIFLPILASM AQAICLHPLY VMLPCTLATS LAFMLPVATP PNAIVFSFGD LKVLDMARAG FLLNIIGVLI IALAINSWGI PLFSLHSFPS WAQSNTTAQC LPSLANTTTP SP
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