About Chromobox protein homolog 3
Chromobox protein homolog 3 (CBX3) is a protein
from Homo sapiens identified by UniProt accession
Q13185, 183 residues long.
MolForge cross-references it against 0 known binders and
280 disease associations.
Target properties
| Protein name | Chromobox protein homolog 3 |
|---|
| UniProt accession | Q13185 |
|---|
| Gene | CBX3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 183 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (280)
Diseases linked to this target (Open Targets).
- endometrial cancer · score 0.25
- BMI-adjusted waist-hip ratio · score 0.21
- BMI-adjusted waist circumference · score 0.21
- physical activity measurement · score 0.20
- body height · score 0.20
- smoking behavior · score 0.19
- waist-hip ratio · score 0.19
- endometriosis · score 0.18
- triglyceride measurement · score 0.18
- age at assessment · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13185-F1 | alphafold | PREDICTED | 75.41 | — |
Amino-acid sequence (183 residues)
MASNKTTLQK MGKKQNGKSK KVEEAEPEEF VVEKVLDRRV VNGKVEYFLK WKGFTDADNT WEPEENLDCP ELIEAFLNSQ KAGKEKDGTK RKSLSDSESD DSKSKKKRDA ADKPRGFARG LDPERIIGAT DSSGELMFLM KWKDSDEADL VLAKEANMKC PQIVIAFYEE RLTWHSCPED EAQ
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