About G protein pathway suppressor 2
G protein pathway suppressor 2 (GPS2) is a protein
from Homo sapiens identified by UniProt accession
Q13227, 327 residues long.
MolForge cross-references it against 0 known binders and
73 disease associations.
Target properties
| Protein name | G protein pathway suppressor 2 |
|---|
| UniProt accession | Q13227 |
|---|
| Gene | GPS2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 327 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (73)
Diseases linked to this target (Open Targets).
- Faundes-Banka syndrome · score 0.46
- viral disease · score 0.37
- neurodegenerative disease · score 0.30
- breast adenocarcinoma · score 0.24
- alkaline phosphatase measurement · score 0.19
- self reported educational attainment · score 0.15
- venous thromboembolism · score 0.14
- endometrial cancer · score 0.14
- neoplasm · score 0.09
- blood phosphate measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13227-F1 | alphafold | PREDICTED | 62.21 | — |
Amino-acid sequence (327 residues)
MPALLERPKL SNAMARALHR HIMMERERKR QEEEEVDKMM EQKMKEEQER RKKKEMEERM SLEETKEQIL KLEEKLLALQ EEKHQLFLQL KKVLHEEEKR RRKEQSDLTT LTSAAYQQSL TVHTGTHLLS MQGSPGGHNR PGTLMAADRA KQMFGPQVLT TRHYVGSAAA FAGTPEHGQF QGSPGGAYGT AQPPPHYGPT QPAYSPSQQL RAPSAFPAVQ YLSQPQPQPY AVHGHFQPTQ TGFLQPGGAL SLQKQMEHAN QQTGFSDSSS LRPMHPQALH PAPGLLASPQ LPVQMQPAGK SGFAATSQPG PRLPFIQHSQ NPRFYHK
Explore G protein pathway suppressor 2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets