About Methanethiol oxidase
Methanethiol oxidase (SELENBP1) is a protein
from Homo sapiens identified by UniProt accession
Q13228, 472 residues long.
MolForge cross-references it against 0 known binders and
210 disease associations.
Target properties
| Protein name | Methanethiol oxidase |
|---|
| UniProt accession | Q13228 |
|---|
| Gene | SELENBP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 472 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (210)
Diseases linked to this target (Open Targets).
- extraoral halitosis due to methanethiol oxidase deficiency · score 0.64
- Red cell distribution width · score 0.34
- protein measurement · score 0.24
- serum copper measurement · score 0.23
- genetic disorder · score 0.12
- neoplasm · score 0.11
- schizophrenia · score 0.10
- lung adenocarcinoma · score 0.09
- non-small cell lung carcinoma · score 0.08
- lymphocyte count · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13228-F1 | alphafold | PREDICTED | 96.64 | — |
Amino-acid sequence (472 residues)
MATKCGNCGP GYSTPLEAMK GPREEIVYLP CIYRNTGTEA PDYLATVDVD PKSPQYCQVI HRLPMPNLKD ELHHSGWNTC SSCFGDSTKS RTKLVLPSLI SSRIYVVDVG SEPRAPKLHK VIEPKDIHAK CELAFLHTSH CLASGEVMIS SLGDVKGNGK GGFVLLDGET FEVKGTWERP GGAAPLGYDF WYQPRHNVMI STEWAAPNVL RDGFNPADVE AGLYGSHLYV WDWQRHEIVQ TLSLKDGLIP LEIRFLHNPD AAQGFVGCAL SSTIQRFYKN EGGTWSVEKV IQVPPKKVKG WLLPEMPGLI TDILLSLDDR FLYFSNWLHG DLRQYDISDP QRPRLTGQLF LGGSIVKGGP VQVLEDEELK SQPEPLVVKG KRVAGGPQMI QLSLDGKRLY ITTSLYSAWD KQFYPDLIRE GSVMLQVDVD TVKGGLKLNP NFLVDFGKEP LGPALAHELR YPGGDCSSDI WI
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