Nucleoside diphosphate kinase C (NME3)

About Nucleoside diphosphate kinase C

Nucleoside diphosphate kinase C (NME3) is a protein from Homo sapiens identified by UniProt accession Q13232, 169 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.

Target properties

Protein name	Nucleoside diphosphate kinase C
UniProt accession	Q13232
Gene	NME3
Organism	Homo sapiens
Length	169 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (43)

Diseases linked to this target (Open Targets).

atrial flutter · score 0.09
atrial fibrillation · score 0.09
sex hormone-binding globulin measurement · score 0.06
IGF-1 measurement · score 0.03
appendicular lean mass · score 0.03
lean body mass · score 0.03
sitting height measurement · score 0.03
body height · score 0.03
cortical thickness · score 0.03
blood metabolite measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q13232-F1	alphafold	PREDICTED	92.29	—

Amino-acid sequence (169 residues)

MICLVLTIFA NLFPAACTGA HERTFLAVKP DGVQRRLVGE IVRRFERKGF KLVALKLVQA SEELLREHYA ELRERPFYGR LVKYMASGPV VAMVWQGLDV VRTSRALIGA TNPADAPPGT IRGDFCIEVG KNLIHGSDSV ESARREIALW FRADELLCWE DSAGHWLYE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards