About Src-like-adapter
Src-like-adapter (SLA) is a protein
from Homo sapiens identified by UniProt accession
Q13239, 276 residues long.
MolForge cross-references it against 0 known binders and
66 disease associations.
Target properties
| Protein name | Src-like-adapter |
|---|
| UniProt accession | Q13239 |
|---|
| Gene | SLA |
|---|
| Organism | Homo sapiens |
|---|
| Length | 276 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (66)
Diseases linked to this target (Open Targets).
- platelet count · score 0.43
- eosinophil percentage of leukocytes · score 0.36
- FEV/FVC ratio · score 0.36
- blood protein measurement · score 0.34
- eosinophil count · score 0.32
- cortical thickness · score 0.29
- cortical surface area measurement · score 0.28
- brain measurement · score 0.24
- monocyte count · score 0.24
- familial thyroid dyshormonogenesis · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13239-F1 | alphafold | PREDICTED | 74.45 | — |
Amino-acid sequence (276 residues)
MGNSMKSTPA PAERPLPNPE GLDSDFLAVL SDYPSPDISP PIFRRGEKLR VISDEGGWWK AISLSTGRES YIPGICVARV YHGWLFEGLG RDKAEELLQL PDTKVGSFMI RESETKKGFY SLSVRHRQVK HYRIFRLPNN WYYISPRLTF QCLEDLVNHY SEVADGLCCV LTTPCLTQST AAPAVRASSS PVTLRQKTVD WRRVSRLQED PEGTENPLGV DESLFSYGLR ESIASYLSLT SEDNTSFDRK KKSISLMYGG SKRKSSFFSS PPYFED
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