Battenin (CLN3)

About Battenin

Battenin (CLN3) is a protein from Homo sapiens identified by UniProt accession Q13286, 438 residues long. MolForge cross-references it against 0 known binders and 297 disease associations.

Target properties

Protein name	Battenin
UniProt accession	Q13286
Gene	CLN3
Organism	Homo sapiens
Length	438 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (297)

Diseases linked to this target (Open Targets).

neuronal ceroid lipofuscinosis 3 · score 0.83
CLN3 disease · score 0.80
neuronal ceroid lipofuscinosis · score 0.67
retinitis pigmentosa · score 0.64
Retinal dystrophy · score 0.58
genetic disorder · score 0.53
Cone rod dystrophy · score 0.44
cone-rod dystrophy · score 0.43
platelet count · score 0.24
mean platelet volume · score 0.23

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q13286-F1	alphafold	PREDICTED	81.48	—

Amino-acid sequence (438 residues)

MGGCAGSRRR FSDSEGEETV PEPRLPLLDH QGAHWKNAVG FWLLGLCNNF SYVVMLSAAH DILSHKRTSG NQSHVDPGPT PIPHNSSSRF DCNSVSTAAV LLADILPTLV IKLLAPLGLH LLPYSPRVLV SGICAAGSFV LVAFSHSVGT SLCGVVFASI SSGLGEVTFL SLTAFYPRAV ISWWSSGTGG AGLLGALSYL GLTQAGLSPQ QTLLSMLGIP ALLLASYFLL LTSPEAQDPG GEEEAESAAR QPLIRTEAPE SKPGSSSSLS LRERWTVFKG LLWYIVPLVV VYFAEYFINQ GLFELLFFWN TSLSHAQQYR WYQMLYQAGV FASRSSLRCC RIRFTWALAL LQCLNLVFLL ADVWFGFLPS IYLVFLIILY EGLLGGAAYV NTFHNIALET SDEHREFAMA ATCISDTLGI SLSGLLALPL HDFLCQLS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards