N-myc-interactor (NMI)

About N-myc-interactor

N-myc-interactor (NMI) is a protein from Homo sapiens identified by UniProt accession Q13287, 307 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.

Target properties

Protein name	N-myc-interactor
UniProt accession	Q13287
Gene	NMI
Organism	Homo sapiens
Length	307 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (46)

Diseases linked to this target (Open Targets).

severe acute respiratory syndrome · score 0.37
type 2 diabetes mellitus · score 0.36
blood protein measurement · score 0.34
tumor necrosis factor-inducible gene 6 protein measurement · score 0.23
urinary metabolite measurement · score 0.18
neurofibrillary tangles measurement · score 0.16
cortical surface area measurement · score 0.15
attention deficit hyperactivity disorder · score 0.14
antisocial behaviour measurement · score 0.14
substance abuse · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q13287-F1	alphafold	PREDICTED	81.98	—

Amino-acid sequence (307 residues)

MEADKDDTQQ ILKEHSPDEF IKDEQNKGLI DEITKKNIQL KKEIQKLETE LQEATKEFQI KEDIPETKMK FLSVETPEND SQLSNISCSF QVSSKVPYEI QKGQALITFE KEEVAQNVVS MSKHHVQIKD VNLEVTAKPV PLNSGVRFQV YVEVSKMKIN VTEIPDTLRE DQMRDKLELS FSKSRNGGGE VDRVDYDRQS GSAVITFVEI GVADKILKKK EYPLYINQTC HRVTVSPYTE IHLKKYQIFS GTSKRTVLLT GMEGIQMDEE IVEDLINIHF QRAKNGGGEV DVVKCSLGQP HIAYFEE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards