Cyclin-dependent kinase 5 activator 2 (CDK5R2)

About Cyclin-dependent kinase 5 activator 2

Cyclin-dependent kinase 5 activator 2 (CDK5R2) is a protein from Homo sapiens identified by UniProt accession Q13319, 367 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.

Target properties

Protein name	Cyclin-dependent kinase 5 activator 2
UniProt accession	Q13319
Gene	CDK5R2
Organism	Homo sapiens
Length	367 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q13319-F1	alphafold	PREDICTED	67.59	—

Amino-acid sequence (367 residues)

MGTVLSLSPA SSAKGRRPGG LPEEKKKAPP AGDEALGGYG APPVGKGGKG ESRLKRPSVL ISALTWKRLV AASAKKKKGS KKVTPKPAST GPDPLVQQRN RENLLRKGRD PPDGGGTAKP LAVPVPTVPA AAATCEPPSG GSAAAQPPGS GGGKPPPPPP PAPQVAPPVP GGSPRRVIVQ ASTGELLRCL GDFVCRRCYR LKELSPGELV GWFRGVDRSL LLQGWQDQAF ITPANLVFVY LLCRESLRGD ELASAAELQA AFLTCLYLAY SYMGNEISYP LKPFLVEPDK ERFWQRCLRL IQRLSPQMLR LNADPHFFTQ VFQDLKNEGE AAASGGGPPS GGAPAASSAA RDSCAAGTKH WTMNLDR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards