About Interferon-induced protein with tetratricopeptide repeats 5
Interferon-induced protein with tetratricopeptide repeats 5 (IFIT5) is a protein
from Homo sapiens identified by UniProt accession
Q13325, 482 residues long.
MolForge cross-references it against 0 known binders and
63 disease associations.
Target properties
| Protein name | Interferon-induced protein with tetratricopeptide repeats 5 |
|---|
| UniProt accession | Q13325 |
|---|
| Gene | IFIT5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 482 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (63)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.08
- body height · score 0.06
- coronary artery disease · score 0.03
- myocardial infarction · score 0.03
- neutrophil count · score 0.03
- C-reactive protein measurement · score 0.03
- leukocyte count · score 0.03
- myeloid white cell count · score 0.03
- Sepsis · score 0.02
- Abdominal Aortic Aneurysm · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13325-F1 | alphafold | PREDICTED | 92.28 | — |
Amino-acid sequence (482 residues)
MSEIRKDTLK AILLELECHF TWNLLKEDID LFEVEDTIGQ QLEFLTTKSR LALYNLLAYV KHLKGQNKDA LECLEQAEEI IQQEHSDKEE VRSLVTWGNY AWVYYHMDQL EEAQKYTGKI GNVCKKLSSP SNYKLECPET DCEKGWALLK FGGKYYQKAK AAFEKALEVE PDNPEFNIGY AITVYRLDDS DREGSVKSFS LGPLRKAVTL NPDNSYIKVF LALKLQDVHA EAEGEKYIEE ILDQISSQPY VLRYAAKFYR RKNSWNKALE LLKKALEVTP TSSFLHHQMG LCYRAQMIQI KKATHNRPKG KDKLKVDELI SSAIFHFKAA MERDSMFAFA YTDLANMYAE GGQYSNAEDI FRKALRLENI TDDHKHQIHY HYGRFQEFHR KSENTAIHHY LEALKVKDRS PLRTKLTSAL KKLSTKRLCH NALDVQSLSA LGFVYKLEGE KRQAAEYYEK AQKIDPENAE FLTALCELRL SI
Explore Interferon-induced protein with tetratricopeptide repeats 5 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets