About MAGUK p55 subfamily member 3
MAGUK p55 subfamily member 3 (MPP3) is a protein
from Homo sapiens identified by UniProt accession
Q13368, 585 residues long.
MolForge cross-references it against 0 known binders and
52 disease associations.
Target properties
| Protein name | MAGUK p55 subfamily member 3 |
|---|
| UniProt accession | Q13368 |
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| Gene | MPP3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 585 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (52)
Diseases linked to this target (Open Targets).
- smoking status measurement · score 0.18
- triglyceride measurement · score 0.14
- genetic disorder · score 0.12
- high density lipoprotein cholesterol measurement · score 0.09
- lymphocyte count · score 0.09
- body height · score 0.08
- mean corpuscular volume · score 0.06
- alcohol drinking · score 0.05
- Red cell distribution width · score 0.05
- leukocyte count · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13368-F1 | alphafold | PREDICTED | 78.18 | — |
Amino-acid sequence (585 residues)
MPVLSEDSGL HETLALLTSQ LRPDSNHKEE MGFLRDVFSE KSLSYLMKIH EKLRYYERQS PTPVLHSAVA LAEDVMEELQ AASVHSDERE LLQLLSTPHL RAVLMVHDTV AQKNFDPVLP PLPDNIDEDF DEESVKIVRL VKNKEPLGAT IRRDEHSGAV VVARIMRGGA ADRSGLVHVG DELREVNGIA VLHKRPDEIS QILAQSQGSI TLKIIPATQE EDRLKESKVF MRALFHYNPR EDRAIPCQEA GLPFQRRQVL EVVSQDDPTW WQAKRVGDTN LRAGLIPSKG FQERRLSYRR AAGTLPSPQS LRKPPYDQPC DKETCDCEGY LKGHYVAGLR RSFRLGCRER LGGSQEGKMS SGAESPELLT YEEVARYQHQ PGERPRLVVL IGSLGARLHE LKQKVVAENP QHFGVAVPHT TRPRKSHEKE GVEYHFVSKQ AFEADLHHNK FLEHGEYKEN LYGTSLEAIQ AVMAKNKVCL VDVEPEALKQ LRTSEFKPYI IFVKPAIQEK RKTPPMSPAC EDTAAPFDEQ QQEMAASAAF IDRHYGHLVD AVLVKEDLQG AYSQLKVVLE KLSKDTHWVP VSWVR
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