About Phosducin-like protein
Phosducin-like protein (PDCL) is a protein
from Homo sapiens identified by UniProt accession
Q13371, 301 residues long.
MolForge cross-references it against 0 known binders and
33 disease associations.
Target properties
| Protein name | Phosducin-like protein |
| UniProt accession | Q13371 |
| Gene | PDCL |
| Organism | Homo sapiens |
| Length | 301 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (33)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- head and neck squamous cell carcinoma · score 0.23
- esophageal cancer · score 0.23
- gastric adenocarcinoma · score 0.23
- breast adenocarcinoma · score 0.23
- lymphocyte percentage of leukocytes · score 0.04
- neoplasm · score 0.02
- glioblastoma multiforme · score 0.02
- retinal degeneration · score 0.02
- Allergy · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q13371-F1 | alphafold | PREDICTED | 76.40 | — |
Amino-acid sequence (301 residues)
MTTLDDKLLG EKLQYYYSSS EDEDSDHEDK DRGRCAPASS SVPAEAELAG EGISVNTGPK GVINDWRRFK QLETEQREEQ CREMERLIKK LSMTCRSHLD EEEEQQKQKD LQEKISGKMT LKEFAIMNED QDDEEFLQQY RKQRMEEMRQ QLHKGPQFKQ VFEISSGEGF LDMIDKEQKS IVIMVHIYED GIPGTEAMNG CMICLAAEYP AVKFCKVKSS VIGASSQFTR NALPALLIYK GGELIGNFVR VTDQLGDDFF AVDLEAFLQE FGLLPEKEVL VLTSVRNSAT CHSEDSDLEI D
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