Phosducin-like protein (PDCL)

Homo sapiens — UniProt Q13371

Gene: PDCLHomo sapiensSwissProt reviewed

About Phosducin-like protein

Phosducin-like protein (PDCL) is a protein from Homo sapiens identified by UniProt accession Q13371, 301 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.

Target properties

Protein namePhosducin-like protein
UniProt accessionQ13371
GenePDCL
OrganismHomo sapiens
Length301 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (33)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.50
  • head and neck squamous cell carcinoma · score 0.23
  • esophageal cancer · score 0.23
  • gastric adenocarcinoma · score 0.23
  • breast adenocarcinoma · score 0.23
  • lymphocyte percentage of leukocytes · score 0.04
  • neoplasm · score 0.02
  • glioblastoma multiforme · score 0.02
  • retinal degeneration · score 0.02
  • Allergy · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q13371-F1alphafoldPREDICTED76.40—

Amino-acid sequence (301 residues)

MTTLDDKLLG EKLQYYYSSS EDEDSDHEDK DRGRCAPASS SVPAEAELAG EGISVNTGPK GVINDWRRFK QLETEQREEQ CREMERLIKK LSMTCRSHLD EEEEQQKQKD LQEKISGKMT LKEFAIMNED QDDEEFLQQY RKQRMEEMRQ QLHKGPQFKQ VFEISSGEGF LDMIDKEQKS IVIMVHIYED GIPGTEAMNG CMICLAAEYP AVKFCKVKSS VIGASSQFTR NALPALLIYK GGELIGNFVR VTDQLGDDFF AVDLEAFLQE FGLLPEKEVL VLTSVRNSAT CHSEDSDLEI D

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Quick facts

UniProtQ13371
GenePDCL
OrganismHomo sapiens
Length301
Binders0
Diseases33
View on UniProt