About Putative nucleotidyltransferase MAB21L1
Putative nucleotidyltransferase MAB21L1 (MAB21L1) is a protein
from Homo sapiens identified by UniProt accession
Q13394, 359 residues long.
MolForge cross-references it against 0 known binders and
196 disease associations.
Target properties
| Protein name | Putative nucleotidyltransferase MAB21L1 |
| UniProt accession | Q13394 |
| Gene | MAB21L1 |
| Organism | Homo sapiens |
| Length | 359 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (196)
Diseases linked to this target (Open Targets).
- cerebellar, ocular, craniofacial, and genital syndrome · score 0.64
- Intellectual disability · score 0.37
- Global developmental delay · score 0.37
- Abnormality of the eye · score 0.37
- Abnormality of the genital system · score 0.37
- Cerebellar hypoplasia · score 0.37
- mathematical ability · score 0.29
- genetic disorder · score 0.18
- cognitive function measurement · score 0.15
- self reported educational attainment · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q13394-F1 | alphafold | PREDICTED | 93.90 | — |
Amino-acid sequence (359 residues)
MIAAQAKLVY HLNKYYNEKC QARKAAIAKT IREVCKVVSD VLKEVEVQEP RFISSLNEMD NRYEGLEVIS PTEFEVVLYL NQMGVFNFVD DGSLPGCAVL KLSDGRKRSM SLWVEFITAS GYLSARKIRS RFQTLVAQAV DKCSYRDVVK MVADTSEVKL RIRDRYVVQI TPAFKCTGIW PRSAAHWPLP HIPWPGPNRV AEVKAEGFNL LSKECHSLAG KQSSAESDAW VLQFAEAENR LQMGGCRKKC LSILKTLRDR HLELPGQPLN NYHMKTLVSY ECEKHPRESD WDESCLGDRL NGILLQLISC LQCRRCPHYF LPNLDLFQGK PHSALENAAK QTWRLAREIL TNPKSLEKL
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