Putative nucleotidyltransferase MAB21L1 (MAB21L1)

Homo sapiens — UniProt Q13394

Gene: MAB21L1Homo sapiensSwissProt reviewed

About Putative nucleotidyltransferase MAB21L1

Putative nucleotidyltransferase MAB21L1 (MAB21L1) is a protein from Homo sapiens identified by UniProt accession Q13394, 359 residues long. MolForge cross-references it against 0 known binders and 196 disease associations.

Target properties

Protein namePutative nucleotidyltransferase MAB21L1
UniProt accessionQ13394
GeneMAB21L1
OrganismHomo sapiens
Length359 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (196)

Diseases linked to this target (Open Targets).

  • cerebellar, ocular, craniofacial, and genital syndrome · score 0.64
  • Intellectual disability · score 0.37
  • Global developmental delay · score 0.37
  • Abnormality of the eye · score 0.37
  • Abnormality of the genital system · score 0.37
  • Cerebellar hypoplasia · score 0.37
  • mathematical ability · score 0.29
  • genetic disorder · score 0.18
  • cognitive function measurement · score 0.15
  • self reported educational attainment · score 0.15

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q13394-F1alphafoldPREDICTED93.90—

Amino-acid sequence (359 residues)

MIAAQAKLVY HLNKYYNEKC QARKAAIAKT IREVCKVVSD VLKEVEVQEP RFISSLNEMD NRYEGLEVIS PTEFEVVLYL NQMGVFNFVD DGSLPGCAVL KLSDGRKRSM SLWVEFITAS GYLSARKIRS RFQTLVAQAV DKCSYRDVVK MVADTSEVKL RIRDRYVVQI TPAFKCTGIW PRSAAHWPLP HIPWPGPNRV AEVKAEGFNL LSKECHSLAG KQSSAESDAW VLQFAEAENR LQMGGCRKKC LSILKTLRDR HLELPGQPLN NYHMKTLVSY ECEKHPRESD WDESCLGDRL NGILLQLISC LQCRRCPHYF LPNLDLFQGK PHSALENAAK QTWRLAREIL TNPKSLEKL

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Quick facts

UniProtQ13394
GeneMAB21L1
OrganismHomo sapiens
Length359
Binders0
Diseases196
View on UniProt