About Ubiquitin-conjugating enzyme E2 variant 1
Ubiquitin-conjugating enzyme E2 variant 1 (UBE2V1) is a protein
from Homo sapiens identified by UniProt accession
Q13404, 147 residues long.
MolForge cross-references it against 0 known binders and
88 disease associations.
Target properties
| Protein name | Ubiquitin-conjugating enzyme E2 variant 1 |
|---|
| UniProt accession | Q13404 |
|---|
| Gene | UBE2V1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 147 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (88)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.36
- neurodegenerative disease · score 0.23
- clear cell renal carcinoma · score 0.18
- monocyte percentage of leukocytes · score 0.10
- testosterone measurement · score 0.10
- inflammatory bowel disease · score 0.09
- granulocyte percentage of myeloid white cells · score 0.09
- breast carcinoma · score 0.08
- calf circumference measurement · score 0.07
- colon carcinoma · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13404-F1 | alphafold | PREDICTED | 93.88 | — |
Amino-acid sequence (147 residues)
MAATTGSGVK VPRNFRLLEE LEEGQKGVGD GTVSWGLEDD EDMTLTRWTG MIIGPPRTIY ENRIYSLKIE CGPKYPEAPP FVRFVTKINM NGVNSSNGVV DPRAISVLAK WQNSYSIKVV LQELRRLMMS KENMKLPQPP EGQCYSN
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