About Butyrophilin subfamily 1 member A1
Butyrophilin subfamily 1 member A1 (BTN1A1) is a protein
from Homo sapiens identified by UniProt accession
Q13410, 526 residues long.
MolForge cross-references it against 0 known binders and
89 disease associations.
Target properties
| Protein name | Butyrophilin subfamily 1 member A1 |
|---|
| UniProt accession | Q13410 |
|---|
| Gene | BTN1A1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 526 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (89)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.47
- apolipoprotein B measurement · score 0.25
- total cholesterol measurement · score 0.25
- low density lipoprotein cholesterol measurement · score 0.24
- platelet count · score 0.17
- systolic blood pressure · score 0.15
- self reported educational attainment · score 0.14
- unipolar depression · score 0.14
- mathematical ability · score 0.13
- cutaneous melanoma · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13410-F1 | alphafold | PREDICTED | 84.24 | — |
Amino-acid sequence (526 residues)
MAVFPSSGLP RCLLTLILLQ LPKLDSAPFD VIGPPEPILA VVGEDAELPC RLSPNASAEH LELRWFRKKV SPAVLVHRDG REQEAEQMPE YRGRATLVQD GIAKGRVALR IRGVRVSDDG EYTCFFREDG SYEEALVHLK VAALGSDPHI SMQVQENGEI CLECTSVGWY PEPQVQWRTS KGEKFPSTSE SRNPDEEGLF TVAASVIIRD TSAKNVSCYI QNLLLGQEKK VEISIPASSL PRLTPWIVAV AVILMVLGLL TIGSIFFTWR LYNERPRERR NEFSSKERLL EELKWKKATL HAVDVTLDPD TAHPHLFLYE DSKSVRLEDS RQKLPEKTER FDSWPCVLGR ETFTSGRHYW EVEVGDRTDW AIGVCRENVM KKGFDPMTPE NGFWAVELYG NGYWALTPLR TPLPLAGPPR RVGIFLDYES GDISFYNMND GSDIYTFSNV TFSGPLRPFF CLWSSGKKPL TICPIADGPE RVTVIANAQD LSKEIPLSPM GEDSAPRDAD TLHSKLIPTQ PSQGAP
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