About 28 kDa heat- and acid-stable phosphoprotein
28 kDa heat- and acid-stable phosphoprotein (PDAP1) is a protein
from Homo sapiens identified by UniProt accession
Q13442, 181 residues long.
MolForge cross-references it against 0 known binders and
34 disease associations.
Target properties
| Protein name | 28 kDa heat- and acid-stable phosphoprotein |
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| UniProt accession | Q13442 |
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| Gene | PDAP1 |
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| Organism | Homo sapiens |
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| Length | 181 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (34)
Diseases linked to this target (Open Targets).
- multiple myeloma · score 0.17
- alcohol consumption measurement · score 0.09
- reticulocyte count · score 0.08
- colorectal carcinoma · score 0.07
- mean corpuscular volume · score 0.06
- testosterone measurement · score 0.05
- sex hormone-binding globulin measurement · score 0.05
- alcohol use disorder measurement · score 0.05
- neoplasm · score 0.04
- cancer · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13442-F1 | alphafold | PREDICTED | 76.38 | — |
Amino-acid sequence (181 residues)
MPKGGRKGGH KGRARQYTSP EEIDAQLQAE KQKAREEEEQ KEGGDGAAGD PKKEKKSLDS DESEDEEDDY QQKRKGVEGL IDIENPNRVA QTTKKVTQLD LDGPKELSRR EREEIEKQKA KERYMKMHLA GKTEQAKADL ARLAIIRKQR EEAARKKEEE RKAKDDATLS GKRMQSLSLN K
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