About Calcium/calmodulin-dependent protein kinase type II subunit gamma
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CAMK2G) is a protein
from Homo sapiens identified by UniProt accession
Q13555, 558 residues long.
MolForge cross-references it against 0 known binders and
136 disease associations.
Target properties
| Protein name | Calcium/calmodulin-dependent protein kinase type II subunit gamma |
|---|
| UniProt accession | Q13555 |
|---|
| Gene | CAMK2G |
|---|
| Organism | Homo sapiens |
|---|
| Length | 558 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (14)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (136)
Diseases linked to this target (Open Targets).
- intellectual developmental disorder 59 · score 0.63
- Intellectual disability, severe · score 0.40
- FEV/FVC ratio · score 0.32
- breast adenocarcinoma · score 0.29
- psoriasis · score 0.29
- Generalized hypotonia · score 0.27
- Global developmental delay · score 0.27
- autism · score 0.27
- serum gamma-glutamyl transferase measurement · score 0.26
- type 2 diabetes mellitus · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13555-F1 | alphafold | PREDICTED | 78.39 | — |
Amino-acid sequence (558 residues)
MATTATCTRF TDDYQLFEEL GKGAFSVVRR CVKKTSTQEY AAKIINTKKL SARDHQKLER EARICRLLKH PNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIHQI LESVNHIHQH DIVHRDLKPE NLLLASKCKG AAVKLADFGL AIEVQGEQQA WFGFAGTPGY LSPEVLRKDP YGKPVDIWAC GVILYILLVG YPPFWDEDQH KLYQQIKAGA YDFPSPEWDT VTPEAKNLIN QMLTINPAKR ITADQALKHP WVCQRSTVAS MMHRQETVEC LRKFNARRKL KGAILTTMLV SRNFSAAKSL LNKKSDGGVK KRKSSSSVHL MPQSNNKNSL VSPAQEPAPL QTAMEPQTTV VHNATDGIKG STESCNTTTE DEDLKGRVPE GRSSRDRTAP SAGMQPQPSL CSSAMRKQEI IKITEQLIEA INNGDFEAYT KICDPGLTSF EPEALGNLVE GMDFHKFYFE NLLSKNSKPI HTTILNPHVH VIGEDAACIA YIRLTQYIDG QGRPRTSQSE ETRVWHRRDG KWLNVHYHCS GAPAAPLQ
Explore Calcium/calmodulin-dependent protein kinase type II subunit gamma with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets