About Calcium/calmodulin-dependent protein kinase type II subunit delta
Calcium/calmodulin-dependent protein kinase type II subunit delta (CAMK2D) is a protein
from Homo sapiens identified by UniProt accession
Q13557, 499 residues long.
MolForge cross-references it against 0 known binders and
178 disease associations.
Target properties
| Protein name | Calcium/calmodulin-dependent protein kinase type II subunit delta |
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| UniProt accession | Q13557 |
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| Gene | CAMK2D |
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| Organism | Homo sapiens |
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| Length | 499 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Approved drugs hitting this target (15)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (178)
Diseases linked to this target (Open Targets).
- Neurodevelopmental disorder · score 0.50
- electrocardiography · score 0.47
- atrial fibrillation · score 0.41
- PR interval · score 0.37
- Parkinson disease · score 0.37
- chronic lymphocytic leukemia · score 0.34
- urate measurement · score 0.33
- bone density · score 0.33
- P wave duration · score 0.31
- TPE interval measurement · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13557-F1 | alphafold | PREDICTED | 83.37 | — |
Amino-acid sequence (499 residues)
MASTTTCTRF TDEYQLFEEL GKGAFSVVRR CMKIPTGQEY AAKIINTKKL SARDHQKLER EARICRLLKH PNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI LESVNHCHLN GIVHRDLKPE NLLLASKSKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY LSPEVLRKDP YGKPVDMWAC GVILYILLVG YPPFWDEDQH RLYQQIKAGA YDFPSPEWDT VTPEAKDLIN KMLTINPAKR ITASEALKHP WICQRSTVAS MMHRQETVDC LKKFNARRKL KGAILTTMLA TRNFSAAKSL LKKPDGVKES TESSNTTIED EDVKARKQEI IKVTEQLIEA INNGDFEAYT KICDPGLTAF EPEALGNLVE GMDFHRFYFE NALSKSNKPI HTIILNPHVH LVGDDAACIA YIRLTQYMDG SGMPKTMQSE ETRVWHRRDG KWQNVHFHRS GSPTVPIKPP CIPNGKENFS GGTSLWQNI
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