About Lysosomal-associated transmembrane protein 5
Lysosomal-associated transmembrane protein 5 (LAPTM5) is a protein
from Homo sapiens identified by UniProt accession
Q13571, 262 residues long.
MolForge cross-references it against 0 known binders and
149 disease associations.
Target properties
| Protein name | Lysosomal-associated transmembrane protein 5 |
|---|
| UniProt accession | Q13571 |
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| Gene | LAPTM5 |
|---|
| Organism | Homo sapiens |
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| Length | 262 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (149)
Diseases linked to this target (Open Targets).
- platelet crit · score 0.50
- neutrophil count · score 0.45
- leukocyte count · score 0.43
- myeloid white cell count · score 0.43
- platelet count · score 0.42
- peak expiratory flow · score 0.35
- monocyte count · score 0.34
- eosinophil count · score 0.31
- sum of neutrophil and eosinophil counts · score 0.28
- granulocyte count · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13571-F1 | alphafold | PREDICTED | 69.35 | — |
Amino-acid sequence (262 residues)
MDPRLSTVRQ TCCCFNVRIA TTALAIYHVI MSVLLFIEHS VEVAHGKASC KLSQMGYLRI ADLISSFLLI TMLFIISLSL LIGVVKNREK YLLPFLSLQI MDYLLCLLTL LGSYIELPAY LKLASRSRAS SSKFPLMTLQ LLDFCLSILT LCSSYMEVPT YLNFKSMNHM NYLPSQEDMP HNQFIKMMII FSIAFITVLI FKVYMFKCVW RCYRLIKCMN SVEEKRNSKM LQKVVLPSYE EALSLPSKTP EGGPAPPPYS EV
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