About Interleukin-10 receptor subunit alpha
Interleukin-10 receptor subunit alpha (IL10RA) is a protein
from Homo sapiens identified by UniProt accession
Q13651, 578 residues long.
MolForge cross-references it against 0 known binders and
354 disease associations.
Target properties
| Protein name | Interleukin-10 receptor subunit alpha |
|---|
| UniProt accession | Q13651 |
|---|
| Gene | IL10RA |
|---|
| Organism | Homo sapiens |
|---|
| Length | 578 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (354)
Diseases linked to this target (Open Targets).
- Autosomal recessive early-onset inflammatory bowel disease · score 0.79
- immune dysregulation-inflammatory bowel disease-arthritis-recurrent infections syndrome · score 0.55
- inflammatory bowel disease · score 0.43
- ulcerative colitis · score 0.38
- pancreatic carcinoma · score 0.26
- genetic disorder · score 0.19
- neoplasm · score 0.11
- infection · score 0.10
- infect · score 0.10
- acute myeloid leukemia · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13651-F1 | alphafold | PREDICTED | 61.99 | — |
Amino-acid sequence (578 residues)
MLPCLVVLLA ALLSLRLGSD AHGTELPSPP SVWFEAEFFH HILHWTPIPN QSESTCYEVA LLRYGIESWN SISNCSQTLS YDLTAVTLDL YHSNGYRARV RAVDGSRHSN WTVTNTRFSV DEVTLTVGSV NLEIHNGFIL GKIQLPRPKM APANDTYESI FSHFREYEIA IRKVPGNFTF THKKVKHENF SLLTSGEVGE FCVQVKPSVA SRSNKGMWSK EECISLTRQY FTVTNVIIFF AFVLLLSGAL AYCLALQLYV RRRKKLPSVL LFKKPSPFIF ISQRPSPETQ DTIHPLDEEA FLKVSPELKN LDLHGSTDSG FGSTKPSLQT EEPQFLLPDP HPQADRTLGN REPPVLGDSC SSGSSNSTDS GICLQEPSLS PSTGPTWEQQ VGSNSRGQDD SGIDLVQNSE GRAGDTQGGS ALGHHSPPEP EVPGEEDPAA VAFQGYLRQT RCAEEKATKT GCLEEESPLT DGLGPKFGRC LVDEAGLHPP ALAKGYLKQD PLEMTLASSG APTGQWNQPT EEWSLLALSS CSDLGISDWS FAHDLAPLGC VAAPGGLLGS FNSDLVTLPL ISSLQSSE
Explore Interleukin-10 receptor subunit alpha with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets