About Apolipoprotein F
Apolipoprotein F (APOF) is a protein
from Homo sapiens identified by UniProt accession
Q13790, 326 residues long.
MolForge cross-references it against 0 known binders and
89 disease associations.
Target properties
| Protein name | Apolipoprotein F |
|---|
| UniProt accession | Q13790 |
|---|
| Gene | APOF |
|---|
| Organism | Homo sapiens |
|---|
| Length | 326 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (89)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.21
- cutaneous melanoma · score 0.18
- mathematical ability · score 0.14
- lung adenocarcinoma · score 0.13
- glioblastoma multiforme · score 0.10
- hepatocellular carcinoma · score 0.09
- hypertriglyceridemia 2 · score 0.07
- cholesterol-ester transfer protein deficiency · score 0.06
- Inguinal hernia · score 0.06
- body height · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13790-F1 | alphafold | PREDICTED | 66.22 | — |
Amino-acid sequence (326 residues)
MTGLCGYSAP DMRGLRLIMI PVELLLCYLL LHPVDATSYG KQTNVLMHFP LSLESQTPSS DPLSCQFLHP KSLPGFSHMA PLPKFLVSLA LRNALEEAGC QADVWALQLQ LYRQGGVNAT QVLIQHLRGL QKGRSTERNV SVEALASALQ LLAREQQSTG RVGRSLPTED CENEKEQAVH NVVQLLPGVG TFYNLGTALY YATQNCLGKA RERGRDGAID LGYDLLMTMA GMSGGPMGLA ISAALKPALR SGVQQLIQYY QDQKDANISQ PETTKEGLRA ISDVSDLEET TTLASFISEV VSSAPYWGWA IIKSYDLDPG AGSLEI
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