About ADP-ribosylation factor-related protein 1
ADP-ribosylation factor-related protein 1 (ARFRP1) is a protein
from Homo sapiens identified by UniProt accession
Q13795, 201 residues long.
MolForge cross-references it against 0 known binders and
74 disease associations.
Target properties
| Protein name | ADP-ribosylation factor-related protein 1 |
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| UniProt accession | Q13795 |
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| Gene | ARFRP1 |
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| Organism | Homo sapiens |
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| Length | 201 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (74)
Diseases linked to this target (Open Targets).
- dyskeratosis congenita, autosomal recessive 5 · score 0.15
- neutrophil count · score 0.12
- atopic eczema · score 0.11
- Crohn's disease · score 0.10
- prostate carcinoma · score 0.10
- wheezing · score 0.09
- myeloid white cell count · score 0.09
- platelet count · score 0.09
- inflammatory bowel disease · score 0.08
- type 2 diabetes mellitus · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13795-F1 | alphafold | PREDICTED | 91.09 | — |
Amino-acid sequence (201 residues)
MYTLLSGLYK YMFQKDEYCI LILGLDNAGK TTFLEQSKTR FNKNYKGMSL SKITTTVGLN IGTVDVGKAR LMFWDLGGQE ELQSLWDKYY AECHGVIYVI DSTDEERLAE SKQAFEKVVT SEALCGVPVL VLANKQDVET CLSIPDIKTA FSDCTSKIGR RDCLTQACSA LTGKGVREGI EWMVKCVVRN VHRPPRQRDI T
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