Bleomycin hydrolase (BLMH)

About Bleomycin hydrolase

Bleomycin hydrolase (BLMH) is a protein from Homo sapiens identified by UniProt accession Q13867, 455 residues long. MolForge cross-references it against 0 known binders and 73 disease associations.

Target properties

Protein name	Bleomycin hydrolase
UniProt accession	Q13867
Gene	BLMH
Organism	Homo sapiens
Length	455 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (73)

Diseases linked to this target (Open Targets).

alkaline phosphatase measurement · score 0.29
total cholesterol measurement · score 0.28
blood protein measurement · score 0.28
sex hormone-binding globulin measurement · score 0.27
clear cell renal carcinoma · score 0.18
smoking status measurement · score 0.08
intelligence · score 0.05
body height · score 0.05
breast milk measurement · score 0.04
myxedema · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q13867-F1	alphafold	PREDICTED	98.01	—

Amino-acid sequence (455 residues)

MSSSGLNSEK VAALIQKLNS DPQFVLAQNV GTTHDLLDIC LKRATVQRAQ HVFQHAVPQE GKPITNQKSS GRCWIFSCLN VMRLPFMKKL NIEEFEFSQS YLFFWDKVER CYFFLSAFVD TAQRKEPEDG RLVQFLLMNP ANDGGQWDML VNIVEKYGVI PKKCFPESYT TEATRRMNDI LNHKMREFCI RLRNLVHSGA TKGEISATQD VMMEEIFRVV CICLGNPPET FTWEYRDKDK NYQKIGPITP LEFYREHVKP LFNMEDKICL VNDPRPQHKY NKLYTVEYLS NMVGGRKTLY NNQPIDFLKK MVAASIKDGE AVWFGCDVGK HFNSKLGLSD MNLYDHELVF GVSLKNMNKA ERLTFGESLM THAMTFTAVS EKDDQDGAFT KWRVENSWGE DHGHKGYLCM TDEWFSEYVY EVVVDRKHVP EEVLAVLEQE PIILPAWDPM GALAE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards