About Krueppel-like factor 9
Krueppel-like factor 9 (KLF9) is a protein
from Homo sapiens identified by UniProt accession
Q13886, 244 residues long.
MolForge cross-references it against 0 known binders and
206 disease associations.
Target properties
| Protein name | Krueppel-like factor 9 |
|---|
| UniProt accession | Q13886 |
|---|
| Gene | KLF9 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 244 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (206)
Diseases linked to this target (Open Targets).
- platelet count · score 0.48
- heel bone mineral density · score 0.46
- mean platelet volume · score 0.41
- body mass index · score 0.41
- mathematical ability · score 0.41
- platelet component distribution width · score 0.37
- self reported educational attainment · score 0.35
- neurodegenerative disease · score 0.33
- neutrophil count · score 0.33
- leukocyte count · score 0.32
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13886-F1 | alphafold | PREDICTED | 62.51 | — |
Amino-acid sequence (244 residues)
MSAAAYMDFV AAQCLVSISN RAAVPEHGVA PDAERLRLPE REVTKEHGDP GDTWKDYCTL VTIAKSLLDL NKYRPIQTPS VCSDSLESPD EDMGSDSDVT TESGSSPSHS PEERQDPGSA PSPLSLLHPG VAAKGKHASE KRHKCPYSGC GKVYGKSSHL KAHYRVHTGE RPFPCTWPDC LKKFSRSDEL TRHYRTHTGE KQFRCPLCEK RFMRSDHLTK HARRHTEFHP SMIKRSKKAL ANAL
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