Isopentenyl-diphosphate Delta-isomerase 1 (IDI1)

About Isopentenyl-diphosphate Delta-isomerase 1

Isopentenyl-diphosphate Delta-isomerase 1 (IDI1) is a protein from Homo sapiens identified by UniProt accession Q13907, 227 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.

Target properties

Protein name	Isopentenyl-diphosphate Delta-isomerase 1
UniProt accession	Q13907
Gene	IDI1
Organism	Homo sapiens
Length	227 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (72)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.54
creatinine measurement · score 0.12
chronic kidney disease · score 0.12
neurofibrillary tangles measurement · score 0.11
age-related macular degeneration · score 0.07
X-linked retinal dysplasia · score 0.06
Familial exudative vitreoretinopathy · score 0.06
retinitis pigmentosa · score 0.06
severe early-childhood-onset retinal dystrophy · score 0.05
Familial drusen · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q13907-F1	alphafold	PREDICTED	97.11	—

Amino-acid sequence (227 residues)

MPEINTNHLD KQQVQLLAEM CILIDENDNK IGAETKKNCH LNENIEKGLL HRAFSVFLFN TENKLLLQQR SDAKITFPGC FTNTCCSHPL SNPAELEESD ALGVRRAAQR RLKAELGIPL EEVPPEEINY LTRIHYKAQS DGIWGEHEID YILLVRKNVT LNPDPNEIKS YCYVSKEELK ELLKKAASGE IKITPWFKII AATFLFKWWD NLNHLNQFVD HEKIYRM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards