About Calicin
Calicin (CCIN) is a protein
from Homo sapiens identified by UniProt accession
Q13939, 588 residues long.
MolForge cross-references it against 0 known binders and
85 disease associations.
Target properties
| Protein name | Calicin |
|---|
| UniProt accession | Q13939 |
|---|
| Gene | CCIN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 588 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (85)
Diseases linked to this target (Open Targets).
- azoospermia · score 0.10
- male infertility with teratozoospermia due to single gene mutation · score 0.09
- partial chromosome Y deletion · score 0.07
- spermatogenic failure 65 · score 0.07
- spermatogenic failure 56 · score 0.07
- spermatogenic failure, X-linked, 3 · score 0.07
- spermatogenic failure 40 · score 0.07
- spermatogenic failure 47 · score 0.07
- spermatogenic failure 11 · score 0.07
- spermatogenic failure 10 · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q13939-F1 | alphafold | PREDICTED | 90.46 | — |
Amino-acid sequence (588 residues)
MKLEFTEKNY NSFVLQNLNR QRKRKEYWDM ALSVDNHVFF AHRNVLAAVS PLVRSLISSN DMKTADELFI TIDTSYLSPV TVDQLLDYFY SGKVVISEQN VEELLRGAQY FNTPRLRVHC NDFLIKSICR ANCLRYLFLA ELFELKEVSD VAYSGIRDNF HYWASPEGSM HFMRCPPVIF GRLLRDENLH VLNEDQALSA LINWVYFRKE DREKYFKKFF NYINLNAVSN KTLVFASNKL VGMENTSSHT TLIESVLMDR KQERPCSLLV YQRKGALLDS VVILGGQKAH GQFNDGVFAY IIQENLWMKL SDMPYRAAAL SATSAGRYIY ISGGTTEQIS GLKTAWRYDM DDNSWTKLPD LPIGLVFHTM VTCGGTVYSV GGSIAPRRYV SNIYRYDERK EVWCLAGKMS IPMDGTAVIT KGDRHLYIVT GRCLVKGYIS RVGVVDCFDT STGDVVQCIT FPIEFNHRPL LSFQQDNILC VHSHRQSVEI NLQKVKASKT TTSVPVLPNS CPLDVSHAIC SIGDSKVFVC GGVTTASDVQ TKDYTINPNA FLLDQKTGKW KTLAPPPEAL DCPACCLAKL PCKILQRI
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