Nuclear transcription factor Y subunit gamma (NFYC)

About Nuclear transcription factor Y subunit gamma

Nuclear transcription factor Y subunit gamma (NFYC) is a protein from Homo sapiens identified by UniProt accession Q13952, 458 residues long. MolForge cross-references it against 0 known binders and 58 disease associations.

Target properties

Protein name	Nuclear transcription factor Y subunit gamma
UniProt accession	Q13952
Gene	NFYC
Organism	Homo sapiens
Length	458 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (58)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.54
body height · score 0.18
neoplasm · score 0.05
Chronic Obstructive Asthma · score 0.05
cancer · score 0.04
cyst · score 0.04
lung adenocarcinoma · score 0.03
lymphocyte count · score 0.03
small cell lung carcinoma · score 0.02
non-small cell lung carcinoma · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q13952-F1	alphafold	PREDICTED	49.47	—

Amino-acid sequence (458 residues)

MSTEGGFGGT SSSDAQQSLQ SFWPRVMEEI RNLTVKDFRV QELPLARIKK IMKLDEDVKM ISAEAPVLFA KAAQIFITEL TLRAWIHTED NKRRTLQRND IAMAITKFDQ FDFLIDIVPR DELKPPKRQE EVRQSVTPAE PVQYYFTLAQ QPTAVQVQGQ QQGQQTTSST TTIQPGQIII AQPQQGQTTP VTMQVGEGQQ VQIVQAQPQG QAQQAQSGTG QTMQVMQQII TNTGEIQQIP VQLNAGQLQY IRLAQPVSGT QVVQGQIQTL ATNAQQGQRN ASQGKPRRCL KETLQITQTE VQQGQQQFSQ FTDGQRNSVQ QARVSELTGE AEPREVKATG NSTPCTSSLP TTHPPSHRAG ASCVCCSQPQ QSSTSPPPSD ALQWVVVEVS GTPNQLETHR ELHAPLPGMT SLSPLHPSQQ LYQIQQVTMP AGQDLAQPMF IQSANQPSDG QAPQVTGD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards