Cell adhesion molecule CEACAM7 (CEACAM7)

About Cell adhesion molecule CEACAM7

Cell adhesion molecule CEACAM7 (CEACAM7) is a protein from Homo sapiens identified by UniProt accession Q14002, 265 residues long. MolForge cross-references it against 0 known binders and 172 disease associations.

Target properties

Protein name	Cell adhesion molecule CEACAM7
UniProt accession	Q14002
Gene	CEACAM7
Organism	Homo sapiens
Length	265 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (172)

Diseases linked to this target (Open Targets).

serum carcinoembryonic antigen measurement · score 0.15
ringed hair disease · score 0.08
Griscelli syndrome type 3 · score 0.08
uncombable hair syndrome · score 0.08
gastric carcinoma · score 0.07
Blackfan-Diamond anemia · score 0.07
hyperinsulinism due to INSR deficiency · score 0.07
hypertriglyceridemia 2 · score 0.07
Gorham-Stout disease · score 0.07
Griscelli disease · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q14002-F1	alphafold	PREDICTED	84.13	—

Amino-acid sequence (265 residues)

MGSPSACPYR VCIPWQGLLL TASLLTFWNL PNSAQTNIDV VPFNVAEGKE VLLVVHNESQ NLYGYNWYKG ERVHANYRII GYVKNISQEN APGPAHNGRE TIYPNGTLLI QNVTHNDAGI YTLHVIKENL VNEEVTRQFY VFSEPPKPSI TSNNFNPVEN KDIVVLTCQP ETQNTTYLWW VNNQSLLVSP RLLLSTDNRT LVLLSATKND IGPYECEIQN PVGASRSDPV TLNVRYESVQ ASSPDLSAGT AVSIMIGVLA GMALI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards