Cytochrome c oxidase copper chaperone (COX17)

About Cytochrome c oxidase copper chaperone

Cytochrome c oxidase copper chaperone (COX17) is a protein from Homo sapiens identified by UniProt accession Q14061, 63 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

Target properties

Protein name	Cytochrome c oxidase copper chaperone
UniProt accession	Q14061
Gene	COX17
Organism	Homo sapiens
Length	63 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (38)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.53
blood protein measurement · score 0.10
neoplasm · score 0.03
cancer · score 0.02
head and neck squamous cell carcinoma · score 0.02
non-small cell lung carcinoma · score 0.02
colorectal carcinoma · score 0.02
hepatocellular carcinoma · score 0.02
renal fibrosis · score 0.02
hyperinsulinemic hypoglycemia, familial, 4 · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q14061-F1	alphafold	PREDICTED	72.21	—

Amino-acid sequence (63 residues)

MPGLVDSNPA PPESQEKKPL KPCCACPETK KARDACIIEK GEEHCGHLIE AHKECMRALG FKI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards