Cylicin-2 (CYLC2)

Homo sapiens — UniProt Q14093

Gene: CYLC2Homo sapiensSwissProt reviewed

About Cylicin-2

Cylicin-2 (CYLC2) is a protein from Homo sapiens identified by UniProt accession Q14093, 348 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein nameCylicin-2
UniProt accessionQ14093
GeneCYLC2
OrganismHomo sapiens
Length348 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (17)

Diseases linked to this target (Open Targets).

  • stressful life event measurement · score 0.29
  • depressive symptom measurement · score 0.29
  • age at menarche · score 0.25
  • large artery stroke · score 0.18
  • emotional symptom measurement · score 0.16
  • triglyceride measurement · score 0.12
  • bone density · score 0.05
  • urate measurement · score 0.05
  • visual perception measurement · score 0.05
  • BMI-adjusted waist-hip ratio · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q14093-F1alphafoldPREDICTED49.93—

Amino-acid sequence (348 residues)

MSLPRFQRVN FGPYDNYIPV SELSKKSWNQ QHFALLFPKP QRPGTKRRSK PSQIRDNTVS IIDEEQLRGD RRQPLWMYRS LMRISERPSV YLAARRQPLK PTRTVEVDSK AAEIGKKGED KTTQKDTTDS ESELKQGKKD SKKGKDIEKG KEEKLDAKKD SKKGKKDAEK GKDSATESED EKGGAKKDNK KDKKDSNKGK DSATESEGEK GGTEKDSKKG KKDSKKGKDS AIELQAVKAD EKKDEDGKKD ANKGDESKDA KKDAKEIKKG KKDKKKPSST DSDSKDDVKK ESKKDATKDA KKVAKKDTEK ESADSKKDAK KNAKKDAKKD AKKNAKKDEK KDAKKKGK

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Quick facts

UniProtQ14093
GeneCYLC2
OrganismHomo sapiens
Length348
Binders0
Diseases17
View on UniProt