Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD)

About Heterogeneous nuclear ribonucleoprotein D0

Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) is a protein from Homo sapiens identified by UniProt accession Q14103, 355 residues long. MolForge cross-references it against 0 known binders and 154 disease associations.

Target properties

Protein name	Heterogeneous nuclear ribonucleoprotein D0
UniProt accession	Q14103
Gene	HNRNPD
Organism	Homo sapiens
Length	355 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (154)

Diseases linked to this target (Open Targets).

chronotype measurement · score 0.45
mathematical ability · score 0.42
body height · score 0.42
alkaline phosphatase measurement · score 0.42
platelet crit · score 0.38
self reported educational attainment · score 0.37
body fat percentage · score 0.35
cortical thickness · score 0.30
BMI-adjusted waist circumference · score 0.30
diet measurement · score 0.29

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q14103-F1	alphafold	PREDICTED	62.48	—

Amino-acid sequence (355 residues)

MSEEQFGGDG AAAAATAAVG GSAGEQEGAM VAATQGAAAA AGSGAGTGGG TASGGTEGGS AESEGAKIDA SKNEEDEGHS NSSPRHSEAA TAQREEWKMF IGGLSWDTTK KDLKDYFSKF GEVVDCTLKL DPITGRSRGF GFVLFKESES VDKVMDQKEH KLNGKVIDPK RAKAMKTKEP VKKIFVGGLS PDTPEEKIRE YFGGFGEVES IELPMDNKTN KRRGFCFITF KEEEPVKKIM EKKYHNVGLS KCEIKVAMSK EQYQQQQQWG SRGGFAGRAR GRGGGPSQNW NQGYSNYWNQ GYGNYGYNSQ GYGGYGGYDY TGYNNYYGYG DYSNQQSGYG KVSRRGGHQN SYKPY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards