About Protein DGCR6
Protein DGCR6 (DGCR6) is a protein
from Homo sapiens identified by UniProt accession
Q14129, 220 residues long.
MolForge cross-references it against 0 known binders and
27 disease associations.
Target properties
| Protein name | Protein DGCR6 |
|---|
| UniProt accession | Q14129 |
|---|
| Gene | DGCR6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 220 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (27)
Diseases linked to this target (Open Targets).
- amino acid measurement · score 0.33
- reticulocyte count · score 0.32
- proline measurement · score 0.31
- reticulocyte measurement · score 0.28
- blood metabolite measurement · score 0.19
- serum metabolite measurement · score 0.17
- platelet count · score 0.14
- late-onset Alzheimers disease · score 0.14
- metabolite measurement · score 0.13
- heel bone mineral density · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q14129-F1 | alphafold | PREDICTED | 85.85 | — |
Amino-acid sequence (220 residues)
MERYAGALEE VADGARQQER HYQLLSALQS LVKELPSSFQ QRLSYTTLSD LALALLDGTV FEIVQGLLEI QHLTEKSLYN QRLRLQNEHR VLRQALRQKH QEAQQACRPH NLPVLQAAQQ RELEAVEHRI REEQRAMDQK IVLELDRKVA DQQSTLEKAG VAGFYVTTNP QELMLQMNLL ELIRKLQQRG CWAGKAALGL GGPWQLPAAQ CDQKGSPVPP
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