About Tripartite motif-containing protein 29
Tripartite motif-containing protein 29 (TRIM29) is a protein
from Homo sapiens identified by UniProt accession
Q14134, 588 residues long.
MolForge cross-references it against 0 known binders and
140 disease associations.
Target properties
| Protein name | Tripartite motif-containing protein 29 |
|---|
| UniProt accession | Q14134 |
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| Gene | TRIM29 |
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| Organism | Homo sapiens |
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| Length | 588 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (140)
Diseases linked to this target (Open Targets).
- urinary albumin to creatinine ratio · score 0.29
- urate measurement · score 0.26
- appendicular lean mass · score 0.25
- diastolic blood pressure · score 0.25
- systolic blood pressure · score 0.24
- blood protein measurement · score 0.21
- IGF-1 measurement · score 0.21
- serum urea measurement · score 0.21
- cerebrospinal fluid biomarker measurement · score 0.20
- mean arterial pressure · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q14134-F1 | alphafold | PREDICTED | 61.48 | — |
Amino-acid sequence (588 residues)
MEAADASRSN GSSPEARDAR SPSGPSGSLE NGTKADGKDA KTTNGHGGEA AEGKSLGSAL KPGEGRSALF AGNEWRRPII QFVESGDDKN SNYFSMDSME GKRSPYAGLQ LGAAKKPPVT FAEKGELRKS IFSESRKPTV SIMEPGETRR NSYPRADTGL FSRSKSGSEE VLCDSCIGNK QKAVKSCLVC QASFCELHLK PHLEGAAFRD HQLLEPIRDF EARKCPVHGK TMELFCQTDQ TCICYLCMFQ EHKNHSTVTV EEAKAEKETE LSLQKEQLQL KIIEIEDEAE KWQKEKDRIK SFTTNEKAIL EQNFRDLVRD LEKQKEEVRA ALEQREQDAV DQVKVIMDAL DERAKVLHED KQTREQLHSI SDSVLFLQEF GALMSNYSLP PPLPTYHVLL EGEGLGQSLG NFKDDLLNVC MRHVEKMCKA DLSRNFIERN HMENGGDHRY VNNYTNSFGG EWSAPDTMKR YSMYLTPKGG VRTSYQPSSP GRFTKETTQK NFNNLYGTKG NYTSRVWEYS SSIQNSDNDL PVVQGSSSFS LKGYPSLMRS QSPKAQPQTW KSGKQTMLSH YRPFYVNKGN GIGSNEAP
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