Protein FAM53B (FAM53B)

About Protein FAM53B

Protein FAM53B (FAM53B) is a protein from Homo sapiens identified by UniProt accession Q14153, 422 residues long. MolForge cross-references it against 0 known binders and 165 disease associations.

Target properties

Protein name	Protein FAM53B
UniProt accession	Q14153
Gene	FAM53B
Organism	Homo sapiens
Length	422 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (165)

Diseases linked to this target (Open Targets).

lymphocyte count · score 0.49
basophil count · score 0.49
neutrophil count · score 0.49
mean platelet volume · score 0.48
leukocyte count · score 0.46
body height · score 0.46
balding measurement · score 0.44
myeloid white cell count · score 0.41
neuroimaging measurement · score 0.40
serum gamma-glutamyl transferase measurement · score 0.40

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q14153-F1	alphafold	PREDICTED	52.39	—

Amino-acid sequence (422 residues)

MVMVLSESLS TRGADSIACG TFSRELHTPK KMSQGPTLFS CGIMENDRWR DLDRKCPLQI DQPSTSIWEC LPEKDSSLWH REAVTACAVT SLIKDLSISD HNGNPSAPPS KRQCRSLSFS DEMSSCRTSW RPLGSKVWTP VEKRRCYSGG SVQRYSNGFS TMQRSSSFSL PSRANVLSSP CDQAGLHHRF GGQPCQGVPG SAPCGQAGDT WSPDLHPVGG GRLDLQRSLS CSHEQFSFVE YCPPSANSTP ASTPELARRS SGLSRSRSQP CVLNDKKVGV KRRRPEEVQE QRPSLDLAKM AQNCQTFSSL SCLSAGTEDC GPQSPFARHV SNTRAWTALL SASGPGGRTP AGTPVPEPLP PSFDDHLACQ EDLSCEESDS CALDEDCGRR AEPAAAWRDR GAPGNSLCSL DGELDIEQIE KN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards