About Malectin
Malectin (MLEC) is a protein
from Homo sapiens identified by UniProt accession
Q14165, 292 residues long.
MolForge cross-references it against 0 known binders and
66 disease associations.
Target properties
| Protein name | Malectin |
|---|
| UniProt accession | Q14165 |
|---|
| Gene | MLEC |
|---|
| Organism | Homo sapiens |
|---|
| Length | 292 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (66)
Diseases linked to this target (Open Targets).
- erythrocyte count · score 0.20
- reticulocyte count · score 0.17
- reticulocyte measurement · score 0.14
- serum metabolite measurement · score 0.13
- schizophrenia · score 0.13
- platelet count · score 0.12
- vital capacity · score 0.08
- red blood cell density measurement · score 0.07
- metabolite measurement · score 0.07
- unipolar depression · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q14165-F1 | alphafold | PREDICTED | 80.30 | — |
Amino-acid sequence (292 residues)
MLGAWAVEGT AVALLRLLLL LLPPAIRGPG LGVAGVAGAA GAGLPESVIW AVNAGGEAHV DVHGIHFRKD PLEGRVGRAS DYGMKLPILR SNPEDQILYQ TERYNEETFG YEVPIKEEGD YVLVLKFAEV YFAQSQQKVF DVRLNGHVVV KDLDIFDRVG HSTAHDEIIP MSIRKGKLSV QGEVSTFTGK LYIEFVKGYY DNPKVCALYI MAGTVDDVPK LQPHPGLEKK EEEEEEEEYD EGSNLKKQTN KNRVQSGPRT PNPYASDNSS LMFPILVAFG VFIPTLFCLC RL
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