About Protein BTG3
Protein BTG3 (BTG3) is a protein
from Homo sapiens identified by UniProt accession
Q14201, 252 residues long.
MolForge cross-references it against 0 known binders and
711 disease associations.
Target properties
| Protein name | Protein BTG3 |
|---|
| UniProt accession | Q14201 |
|---|
| Gene | BTG3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 252 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (711)
Diseases linked to this target (Open Targets).
- intelligence · score 0.37
- feeling emotionally hurt measurement · score 0.29
- ulcerative colitis · score 0.25
- breast milk measurement · score 0.25
- nasopharyngeal neoplasm · score 0.25
- neutrophil count · score 0.16
- FEV/FVC ratio · score 0.16
- Systemic lupus erythematosus · score 0.11
- autoimmune thrombocytopenic purpura · score 0.10
- hepatocellular carcinoma · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q14201-F1 | alphafold | PREDICTED | 71.08 | — |
Amino-acid sequence (252 residues)
MKNEIAAVVF FFTRLVRKHD KLKKEAVERF AEKLTLILQE KYKNHWYPEK PSKGQAYRCI RVNKFQRVDP DVLKACENSC ILYSDLGLPK ELTLWVDPCE VCCRYGEKNN AFIVASFENK DENKDEISRK VTRALDKVTS DYHSGSSSSD EETSKEMEVK PSSVTAAASP VYQISELIFP PLPMWHPLPR KKPGMYRGNG HQNHYPPPVP FGYPNQGRKN KPYRPIPVTW VPPPGMHCDR NHWINPHMLA PH
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