About Calcipressin-2
Calcipressin-2 (RCAN2) is a protein
from Homo sapiens identified by UniProt accession
Q14206, 197 residues long.
MolForge cross-references it against 0 known binders and
80 disease associations.
Target properties
| Protein name | Calcipressin-2 |
|---|
| UniProt accession | Q14206 |
|---|
| Gene | RCAN2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 197 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (80)
Diseases linked to this target (Open Targets).
- body mass index · score 0.47
- PR interval · score 0.36
- nose morphology measurement · score 0.31
- gut microbiome measurement · score 0.31
- neurodegenerative disease · score 0.26
- Obesity · score 0.08
- non-alcoholic fatty liver disease · score 0.07
- neoplasm · score 0.05
- atypical teratoid rhabdoid tumor · score 0.04
- hepatocellular carcinoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q14206-F1 | alphafold | PREDICTED | 79.24 | — |
Amino-acid sequence (197 residues)
MPAPSMDCDV STLVACVVDV EVFTNQEVKE KFEGLFRTYD DCVTFQLFKS FRRVRINFSN PKSAARARIE LHETQFRGKK LKLYFAQVQT PETDGDKLHL APPQPAKQFL ISPPSSPPVG WQPINDATPV LNYDLLYAVA KLGPGEKYEL HAGTESTPSV VVHVCDSDIE EEEDPKTSPK PKIIQTRRPG LPPSVSN
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