About Ensconsin
Ensconsin (MAP7) is a protein
from Homo sapiens identified by UniProt accession
Q14244, 749 residues long.
MolForge cross-references it against 0 known binders and
157 disease associations.
Target properties
| Protein name | Ensconsin |
|---|
| UniProt accession | Q14244 |
|---|
| Gene | MAP7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 749 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (157)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.40
- cystatin C measurement · score 0.28
- multiple sclerosis · score 0.23
- lysosomal storage disease · score 0.23
- Alzheimer disease · score 0.23
- Parkinson disease · score 0.23
- platelet count · score 0.14
- azoospermia · score 0.10
- partial chromosome Y deletion · score 0.09
- spermatogenic failures 50 · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q14244-F1 | alphafold | PREDICTED | 60.73 | — |
Amino-acid sequence (749 residues)
MAELGAGGDG HRGGDGAVRS ETAPDSYKVQ DKKNASSRPA SAISGQNNNH SGNKPDPPPV LRVDDRQRLA RERREEREKQ LAAREIVWLE REERARQHYE KHLEERKKRL EEQRQKEERR RAAVEEKRRQ RLEEDKERHE AVVRRTMERS QKPKQKHNRW SWGGSLHGSP SIHSADPDRR SVSTMNLSKY VDPVISKRLS SSSATLLNSP DRARRLQLSP WESSVVNRLL TPTHSFLARS KSTAALSGEA ASCSPIIMPY KAAHSRNSMD RPKLFVTPPE GSSRRRIIHG TASYKKERER ENVLFLTSGT RRAVSPSNPK ARQPARSRLW LPSKSLPHLP GTPRPTSSLP PGSVKAAPAQ VRPPSPGNIR PVKREVKVEP EKKDPEKEPQ KVANEPSLKG RAPLVKVEEA TVEERTPAEP EVGPAAPAMA PAPASAPAPA SAPAPAPVPT PAMVSAPSST VNASASVKTS AGTTDPEEAT RLLAEKRRLA REQREKEERE RREQEELERQ KREELAQRVA EERTTRREEE SRRLEAEQAR EKEEQLQRQA EERALREREE AERAQRQKEE EARVREEAER VRQEREKHFQ REEQERLERK KRLEEIMKRT RRTEATDKKT SDQRNGDIAK GALTGGTEVS ALPCTTNAPG NGKPVGSPHV VTSHQSKVTV ESTPDLEKQP NENGVSVQNE NFEEIINLPI GSKPSRLDVT NSESPEIPLN PILAFDDEGT LGPLPQVDGV QTQQTAEVI
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